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Sequencing the B Cell Receptor Repertoires of Antibody-Deficient Individuals With and Without Infection Susceptibility

PURPOSE: Most individuals with antibody deficiency (hypogammaglobulinemia) need immunoglobulin replacement therapy (IgG-RT) from healthy plasma donors to stay clear of infections. However, a small subset of hypogammaglobulinemic patients do not require this substitution therapy. We set out to invest...

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Detalles Bibliográficos
Autores principales: Lim, Yoong Wearn, Ramirez, Neftali Jose, Asensio, Michael A., Chiang, Yao, Müller, Gabriele, Mrovecova, Pavla, Mitsuiki, Noriko, Krausz, Máté, Camacho-Ordonez, Nadezhda, Warnatz, Klaus, Adler, Adam S., Grimbacher, Bodo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276080/
https://www.ncbi.nlm.nih.gov/pubmed/36826743
http://dx.doi.org/10.1007/s10875-023-01448-0