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Leveraging family history data to disentangle time-varying effects on disease risk using lifecourse mendelian randomization

Lifecourse Mendelian randomization is a causal inference technique which harnesses genetic variants with time-varying effects to develop insight into the influence of age-dependent lifestyle factors on disease risk. Here, we apply this approach to evaluate whether childhood body size has a direct co...

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Detalles Bibliográficos
Autores principales: Richardson, Tom G, Urquijo, Helena, Holmes, Michael V, Davey Smith, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276123/
https://www.ncbi.nlm.nih.gov/pubmed/37156976
http://dx.doi.org/10.1007/s10654-023-01001-8