Human TMEM2 is not a catalytic hyaluronidase, but a regulator of hyaluronan metabolism via HYBID (KIAA1199/CEMIP) and HAS2 expression

Cutaneous hyaluronan (HA) is depolymerized to intermediate sizes in the extracellular matrix, and further fragmented in the regional lymph nodes. Previously, we showed that the HA-binding protein involved in HA depolymerization (HYBID), also known as KIAA1199/CEMIP, is responsible for the first step...

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Detalles Bibliográficos
Autores principales: Sato, Shinya, Miyazaki, Megumi, Fukuda, Shinji, Mizutani, Yukiko, Mizukami, Yoichi, Higashiyama, Shigeki, Inoue, Shintaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276149/
https://www.ncbi.nlm.nih.gov/pubmed/37196767
http://dx.doi.org/10.1016/j.jbc.2023.104826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276149/
https://www.ncbi.nlm.nih.gov/pubmed/37196767
http://dx.doi.org/10.1016/j.jbc.2023.104826

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