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Deficiency of miR-409-3p improves myocardial neovascularization and function through modulation of DNAJB9/p38 MAPK signaling

Angiogenesis is critical for tissue repair following myocardial infarction (MI), which is exacerbated under insulin resistance or diabetes. MicroRNAs are regulators of angiogenesis. We examined the metabolic regulation of miR-409-3p in post-infarct angiogenesis. miR-409-3p was increased in patients...

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Detalles Bibliográficos
Autores principales: Bestepe, Furkan, Fritsche, Colette, Lakhotiya, Kartik, Niosi, Carolyn E., Ghanem, George F., Martin, Gregory L., Pal-Ghosh, Ruma, Becker-Greene, Dakota, Weston, James, Hollan, Ivana, Risnes, Ivar, Rynning, Stein Erik, Solheim, Liv Heidi, Feinberg, Mark W., Blanton, Robert M., Icli, Basak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276151/
https://www.ncbi.nlm.nih.gov/pubmed/37332476
http://dx.doi.org/10.1016/j.omtn.2023.05.021