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Evaluating the effect of acute diesel exhaust particle exposure on P-glycoprotein efflux transporter in the blood–brain barrier co-cultured with microglia

A growing public health concern, chronic Diesel Exhaust Particle (DEP) exposure is a heavy risk factor for the development of neurodegenerative diseases like Alzheimer’s (AD). Considered the brain’s first line of defense, the Blood–Brain Barrier (BBB) and perivascular microglia work in tandem to pro...

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Detalles Bibliográficos
Autores principales: Aquino, Grace V., Dabi, Amjad, Odom, Gabriel J., Lavado, Ramon, Nunn, Kaitlin, Thomas, Kathryn, Schackmuth, Bennett, Shariff, Nazeel, Jarajapu, Manogna, Pluto, Morgan, Miller, Sara R., Eller, Leah, Pressley, Justin, Patel, Rishi R., Black, Jeffrey, Bruce, Erica D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276163/
https://www.ncbi.nlm.nih.gov/pubmed/37332622
http://dx.doi.org/10.1016/j.crtox.2023.100107