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Ceramide analog C2-cer induces a loss in insulin sensitivity in muscle cells through the salvage/recycling pathway

Ceramides have been shown to play a major role in the onset of skeletal muscle insulin resistance and therefore in the prevalence of type 2 diabetes. However, many of the studies involved in the discovery of deleterious ceramide actions used a nonphysiological, cell-permeable, short-chain ceramide a...

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Detalles Bibliográficos
Autores principales: Bandet, Cécile L., Tan-Chen, Sophie, Ali-Berrada, Sarah, Campana, Mélanie, Poirier, Maxime, Blachnio-Zabielska, Agnieszka, Pais-de-Barros, Jean-Paul, Rouch, Claude, Ferré, Pascal, Foufelle, Fabienne, Le Stunff, Hervé, Hajduch, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276168/
https://www.ncbi.nlm.nih.gov/pubmed/37178918
http://dx.doi.org/10.1016/j.jbc.2023.104815