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Ceramide analog C2-cer induces a loss in insulin sensitivity in muscle cells through the salvage/recycling pathway
Ceramides have been shown to play a major role in the onset of skeletal muscle insulin resistance and therefore in the prevalence of type 2 diabetes. However, many of the studies involved in the discovery of deleterious ceramide actions used a nonphysiological, cell-permeable, short-chain ceramide a...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276168/ https://www.ncbi.nlm.nih.gov/pubmed/37178918 http://dx.doi.org/10.1016/j.jbc.2023.104815 |