Cargando…
Distant sequence regions of JBP1 contribute to J-DNA binding
Base-J (β-D-glucopyranosyloxymethyluracil) is a modified DNA nucleotide that replaces 1% of thymine in kinetoplastid flagellates. The biosynthesis and maintenance of base-J depends on the base-J-binding protein 1 (JBP1) that has a thymidine hydroxylase domain and a J-DNA-binding domain (JDBD). How t...
Autores principales: | de Vries, Ida, Ammerlaan, Danique, Heidebrecht, Tatjana, Celie, Patrick HN, Geerke, Daan P, Joosten, Robbie P, Perrakis, Anastassis |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276184/ https://www.ncbi.nlm.nih.gov/pubmed/37328191 http://dx.doi.org/10.26508/lsa.202302150 |
Ejemplares similares
-
The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1
por: Heidebrecht, Tatjana, et al.
Publicado: (2011) -
Behind Base J: The Roles of JBP1 and JBP2 on Trypanosomatids
por: Assis, Luiz Henrique de Castro, et al.
Publicado: (2023) -
AlphaFill: enriching AlphaFold models with ligands and cofactors
por: Hekkelman, Maarten L., et al.
Publicado: (2022) -
PDB_REDO: constructive validation, more than just looking for errors
por: Joosten, Robbie P., et al.
Publicado: (2012) -
JBP1 and JBP2 are two distinct thymidine hydroxylases involved in J biosynthesis in genomic DNA of African trypanosomes
por: Cliffe, Laura J., et al.
Publicado: (2009)