Tumor-localized catalases can fail to alter tumor growth and transcriptional profiles in subcutaneous syngeneic mouse tumor models

Catalase is an antioxidant enzyme that catalyzes the rapid conversion of hydrogen peroxide to water and oxygen. Use of catalase as a cancer therapeutic has been proposed to reduce oxidative stress and hypoxia in the tumor microenvironment, both activities which are hypothesized to reduce tumor growt...

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Detalles Bibliográficos
Autores principales: Sheen, Allison, Agarwal, Yash, Cheah, Keith M., Cowles, Sarah C., Stinson, Jordan A., Palmeri, Joseph R., Sikes, Hadley D., Wittrup, K. Dane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276214/
https://www.ncbi.nlm.nih.gov/pubmed/37311396
http://dx.doi.org/10.1016/j.redox.2023.102766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276214/
https://www.ncbi.nlm.nih.gov/pubmed/37311396
http://dx.doi.org/10.1016/j.redox.2023.102766

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