Cargando…
Orthogonal approaches required to measure proteasome composition and activity in mammalian brain tissue
Proteasomes are large macromolecular complexes with multiple distinct catalytic activities that are each vital to human brain health and disease. Despite their importance, standardized approaches to investigate proteasomes have not been universally adapted. Here, we describe pitfalls and define stra...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276296/ https://www.ncbi.nlm.nih.gov/pubmed/37172721 http://dx.doi.org/10.1016/j.jbc.2023.104811 |