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Lactate promotes neuronal differentiation of SH-SY5Y cells by lactate-responsive gene sets through NDRG3-dependent and -independent manners

Lactate serves as the major glucose alternative to an energy substrate in the brain. Lactate level is increased in the fetal brain from the middle stage of gestation, indicating the involvement of lactate in brain development and neuronal differentiation. Recent reports show that lactate functions a...

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Detalles Bibliográficos
Autores principales: Xu, Yidan, Kusuyama, Joji, Osana, Shion, Matsuhashi, Satayuki, Li, Longfei, Takada, Hiroaki, Inada, Hitoshi, Nagatomi, Ryoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276297/
https://www.ncbi.nlm.nih.gov/pubmed/37172727
http://dx.doi.org/10.1016/j.jbc.2023.104802