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Integrated Metabolomics and Network Pharmacology to Reveal the Mechanisms of Gandouling Tablets Against Copper-Overload-Induced Neuronal Injury in Rats with Wilson’s Disease

PURPOSE: Gandouling Tablets (GDL), a proprietary Chinese medicine, have shown a preventive effect against Wilson’s disease (WD)-induced neuronal damage in previous studies. However, the potential mechanisms need additional investigation. Combining metabonomics and network pharmacology revealed the G...

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Detalles Bibliográficos
Autores principales: Chen, Li, Xu, Wang-Yang, Chen, Hao, Han, Yan-Quan, Zhang, Yu-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276572/
https://www.ncbi.nlm.nih.gov/pubmed/37333964
http://dx.doi.org/10.2147/DDDT.S409691