Cargando…

Unfolded protein response inhibits KAT2B/MLKL-mediated necroptosis of hepatocytes by promoting BMI1 level to ubiquitinate KAT2B

Unfolded protein response (UPR) plays an important role in the pathogenesis of many liver diseases. BMI1 has a liver protection effect, but whether it participates in the regulation of hepatocyte death through UPR is not well defined. Herein, the endoplasmic reticulum stress model was established by...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Xiaogang, He, Xiongzhi, Qiu, Rongxian, Xie, Xuemei, Zheng, Fengfeng, Chen, Feihua, Hu, Zhenting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276622/
https://www.ncbi.nlm.nih.gov/pubmed/37333449
http://dx.doi.org/10.1515/med-2023-0718