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Unfolded protein response inhibits KAT2B/MLKL-mediated necroptosis of hepatocytes by promoting BMI1 level to ubiquitinate KAT2B
Unfolded protein response (UPR) plays an important role in the pathogenesis of many liver diseases. BMI1 has a liver protection effect, but whether it participates in the regulation of hepatocyte death through UPR is not well defined. Herein, the endoplasmic reticulum stress model was established by...
Autores principales: | Huang, Xiaogang, He, Xiongzhi, Qiu, Rongxian, Xie, Xuemei, Zheng, Fengfeng, Chen, Feihua, Hu, Zhenting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276622/ https://www.ncbi.nlm.nih.gov/pubmed/37333449 http://dx.doi.org/10.1515/med-2023-0718 |
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