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Cannabidiol inhibits Na(v) channels through two distinct binding sites

Cannabidiol (CBD), a major non-psychoactive phytocannabinoid in cannabis, is an effective treatment for some forms of epilepsy and pain. At high concentrations, CBD interacts with a huge variety of proteins, but which targets are most relevant for clinical actions is still unclear. Here we show that...

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Detalles Bibliográficos
Autores principales: Huang, Jian, Fan, Xiao, Jin, Xueqin, Jo, Sooyeon, Zhang, Hanxiong Bear, Fujita, Akie, Bean, Bruce P., Yan, Nieng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276812/
https://www.ncbi.nlm.nih.gov/pubmed/37330538
http://dx.doi.org/10.1038/s41467-023-39307-6