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Cannabidiol inhibits Na(v) channels through two distinct binding sites
Cannabidiol (CBD), a major non-psychoactive phytocannabinoid in cannabis, is an effective treatment for some forms of epilepsy and pain. At high concentrations, CBD interacts with a huge variety of proteins, but which targets are most relevant for clinical actions is still unclear. Here we show that...
Autores principales: | Huang, Jian, Fan, Xiao, Jin, Xueqin, Jo, Sooyeon, Zhang, Hanxiong Bear, Fujita, Akie, Bean, Bruce P., Yan, Nieng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276812/ https://www.ncbi.nlm.nih.gov/pubmed/37330538 http://dx.doi.org/10.1038/s41467-023-39307-6 |
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