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The inhibition mechanism of the SUR2A-containing K(ATP) channel by a regulatory helix
K(ATP) channels are metabolic sensors for intracellular ATP/ADP ratios, play essential roles in many physiological processes, and are implicated in a spectrum of pathological conditions. SUR2A-containing K(ATP) channels differ from other subtypes in their sensitivity to Mg-ADP activation. However, t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276813/ https://www.ncbi.nlm.nih.gov/pubmed/37330603 http://dx.doi.org/10.1038/s41467-023-39379-4 |