Cargando…

Epigenetically modified AP-2α by DNA methyltransferase facilitates glioma immune evasion by upregulating PD-L1 expression

Programmed death-ligand 1 (PD-L1) ensures that tumor cells escape T-cell-mediated tumor immune surveillance. However, gliomas are characteristic of the low immune response and high-resistance therapy, it is necessary to understand molecular regulatory mechanisms in glioblastoma, especially the limit...

Descripción completa

Detalles Bibliográficos
Autores principales: Long, Shengwen, Huang, Guixiang, Ouyang, Mi, Xiao, Kai, Zhou, Hao, Hou, Anyi, Li, Zhiwei, Zhong, Zhe, Zhong, Dongmei, Wang, Qinghao, Xiang, Shuanglin, Ding, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276877/
https://www.ncbi.nlm.nih.gov/pubmed/37330579
http://dx.doi.org/10.1038/s41419-023-05878-x