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The Notch-mediated circuitry in the evolution and generation of new cell lineages: the tooth model

The Notch pathway is an ancient, evolutionary conserved intercellular signaling mechanism that is involved in cell fate specification and proper embryonic development. The Jagged2 gene, which encodes a ligand for the Notch family of receptors, is expressed from the earliest stages of odontogenesis i...

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Detalles Bibliográficos
Autores principales: Mitsiadis, Thimios A., Pagella, Pierfrancesco, Capellini, Terence D., Smith, Moya Meredith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277265/
https://www.ncbi.nlm.nih.gov/pubmed/37330998
http://dx.doi.org/10.1007/s00018-023-04831-7