Soluble CD4 effectively prevents excessive TLR activation of resident macrophages in the onset of sepsis

T lymphopenia, occurring in the early phase of sepsis in response to systemic inflammation, is commonly associated with morbidity and mortality of septic infections. We have previously shown that a sufficient number of T cells is required to constrain Toll-like receptors (TLRs) mediated hyperinflamm...

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Detalles Bibliográficos
Autores principales: Zhang, Sheng-yuan, Xu, Qiu-ping, Shi, Li-na, Li, Shih-wen, Wang, Wei-hong, Wang, Qing-qing, Lu, Liao-xun, Xiao, Hui, Wang, Jun-hong, Li, Feng-ying, Liang, Yin-ming, Gong, Si-tang, Peng, Hao-ran, Zhang, Zheng, Tang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277282/
https://www.ncbi.nlm.nih.gov/pubmed/37332010
http://dx.doi.org/10.1038/s41392-023-01438-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277282/
https://www.ncbi.nlm.nih.gov/pubmed/37332010
http://dx.doi.org/10.1038/s41392-023-01438-z

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