A luminescence-based reporter to study tau secretion reveals overlapping mechanisms for the release of healthy and pathological tau

In Alzheimer’s disease, tau pathology is thought to spread via a prion-like manner along connected neuronal networks. For this to occur, the usually cytosolic tau protein must be secreted via an unconventional mechanism prior to uptake into the connected neuron. While secretion of healthy and pathol...

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Detalles Bibliográficos
Autores principales: Lopez, Dianne Marquez, Maltby, Connor J., Warming, Hannah, Divecha, Nullin, Vargas-Caballero, Mariana, Coldwell, Mark J., Deinhardt, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277490/
https://www.ncbi.nlm.nih.gov/pubmed/37342467
http://dx.doi.org/10.3389/fnins.2023.1196007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277490/
https://www.ncbi.nlm.nih.gov/pubmed/37342467
http://dx.doi.org/10.3389/fnins.2023.1196007

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