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A luminescence-based reporter to study tau secretion reveals overlapping mechanisms for the release of healthy and pathological tau
In Alzheimer’s disease, tau pathology is thought to spread via a prion-like manner along connected neuronal networks. For this to occur, the usually cytosolic tau protein must be secreted via an unconventional mechanism prior to uptake into the connected neuron. While secretion of healthy and pathol...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277490/ https://www.ncbi.nlm.nih.gov/pubmed/37342467 http://dx.doi.org/10.3389/fnins.2023.1196007 |