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Analysis of serum proteomics data identifies a quantitative association between beta-defensin 2 at baseline and clinical response to IL-17 blockade in psoriatic arthritis

OBJECTIVES: Despite several effective targeted therapies, biomarkers that predict whether a patient with psoriatic arthritis (PsA) will respond to a particular treatment are currently lacking. METHODS: We analysed proteomics data from serum samples of nearly 2000 patients with PsA in placebo-control...

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Detalles Bibliográficos
Autores principales: Cardner, Mathias, Tuckwell, Danny, Kostikova, Anna, Forrer, Pascal, Siegel, Richard M, Marti, Alain, Vandemeulebroecke, Marc, Ferrero, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277527/
https://www.ncbi.nlm.nih.gov/pubmed/37321668
http://dx.doi.org/10.1136/rmdopen-2023-003042