CD22 CAR T-cell associated hematologic toxicities, endothelial activation and relationship to neurotoxicity

BACKGROUND: Hematologic toxicities, including coagulopathy, endothelial activation, and cytopenias, with CD19-targeted chimeric antigen receptor (CAR) T-cell therapies correlate with cytokine release syndrome (CRS) and neurotoxicity severity, but little is known about the extended toxicity profiles...

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Detalles Bibliográficos
Autores principales: Jess, Jennifer, Yates, Bonnie, Dulau-Florea, Alina, Parker, Kevin, Inglefield, Jon, Lichtenstein, Dan, Schischlik, Fiorella, Ongkeko, Martin, Wang, Yanyu, Shahani, Shilpa, Cullinane, Ann, Smith, Hannah, Kane, Eli, Little, Lauren, Chen, Dong, Fry, Terry J, Shalabi, Haneen, Wang, Hao-Wei, Satpathy, Ansuman, Lozier, Jay, Shah, Nirali N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277551/
https://www.ncbi.nlm.nih.gov/pubmed/37295816
http://dx.doi.org/10.1136/jitc-2022-005898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277551/
https://www.ncbi.nlm.nih.gov/pubmed/37295816
http://dx.doi.org/10.1136/jitc-2022-005898

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