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Downregulation of interleukin 6 signaling might reduce the risk of periodontitis: a drug target Mendelian randomization study

AIM: Interleukin 6 (IL-6) is considered to play a role in the dysbiotic host response in the development of periodontitis. While the inhibition of the IL-6 receptor using monoclonal antibodies is a well-established therapy for some diseases, so far, its potential benefit in patients with periodontit...

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Detalles Bibliográficos
Autores principales: Nolde, Michael, Alayash, Zoheir, Reckelkamm, Stefan Lars, Kocher, Thomas, Ehmke, Benjamin, Holtfreter, Birte, Baurecht, Hansjörg, Georgakis, Marios K., Baumeister, Sebastian-Edgar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277556/
https://www.ncbi.nlm.nih.gov/pubmed/37342352
http://dx.doi.org/10.3389/fimmu.2023.1160148