A framework for assessing selection and misclassification bias in mendelian randomisation studies: an illustrative example between body mass index and covid-19

Mendelian randomisation (MR) studies, which investigate causal effects of exposures on disease, might be biased by sample selection and misclassification if phenotypes are not measured universally with the same definition in all study populations or participants. For example, in MR analyses of effec...

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Detalles Bibliográficos
Autores principales: Clayton, Gemma L, Gonçalves, Ana, Soares, Goulding, Neil, Borges, Maria Carolina, Holmes, Michael V, Davey, George, Smith, Tilling, Kate, Lawlor, Deborah A, Carter, Alice R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2023
Materias:
Research Methods & Reporting
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277657/
https://www.ncbi.nlm.nih.gov/pubmed/37336561
http://dx.doi.org/10.1136/bmj-2022-072148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277657/
https://www.ncbi.nlm.nih.gov/pubmed/37336561
http://dx.doi.org/10.1136/bmj-2022-072148

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