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Use of multiple polygenic risk scores for distinguishing schizophrenia-spectrum disorder and affective psychosis categories in a first-episode sample; the EU-GEI study

BACKGROUND: Schizophrenia (SZ), bipolar disorder (BD) and depression (D) run in families. This susceptibility is partly due to hundreds or thousands of common genetic variants, each conferring a fractional risk. The cumulative effects of the associated variants can be summarised as a polygenic risk...

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Detalles Bibliográficos
Autores principales: Rodriguez, Victoria, Alameda, Luis, Quattrone, Diego, Tripoli, Giada, Gayer-Anderson, Charlotte, Spinazzola, Edoardo, Trotta, Giulia, Jongsma, Hannah E., Stilo, Simona, La Cascia, Caterina, Ferraro, Laura, La Barbera, Daniele, Lasalvia, Antonio, Tosato, Sarah, Tarricone, Ilaria, Bonora, Elena, Jamain, Stéphane, Selten, Jean-Paul, Velthorst, Eva, de Haan, Lieuwe, Llorca, Pierre-Michel, Arrojo, Manuel, Bobes, Julio, Bernardo, Miguel, Arango, Celso, Kirkbride, James, Jones, Peter B., Rutten, Bart P., Richards, Alexander, Sham, Pak C., O'Donovan, Michael, Van Os, Jim, Morgan, Craig, Di Forti, Marta, Murray, Robin M., Vassos, Evangelos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277719/
https://www.ncbi.nlm.nih.gov/pubmed/35076361
http://dx.doi.org/10.1017/S0033291721005456