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Bioprocess development for universal influenza vaccines based on inactivated split chimeric and mosaic hemagglutinin viruses

Seasonal influenza viruses account for 1 billion infections worldwide every year, including 3–5 million cases of severe illness and up to 650,000 deaths. The effectiveness of current influenza virus vaccines is variable and relies on the immunodominant hemagglutinin (HA) and to a lesser extent on th...

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Detalles Bibliográficos
Autores principales: Puente-Massaguer, Eduard, Beyer, Annika, Loganathan, Madhumathi, Sapse, Iden, Carreño, Juan Manuel, Bajic, Goran, Sun, Weina, Palese, Peter, Krammer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277804/
https://www.ncbi.nlm.nih.gov/pubmed/37342504
http://dx.doi.org/10.3389/fbioe.2023.1097349