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Modulation of the canonical Wnt activity by androgen signaling in prostate epithelial basal stem cells

Both the canonical Wnt and androgen receptor (AR) signaling pathways are important for prostate organogenesis and homeostasis. How they crosstalk to regulate prostate stem cell behaviors remains unclear. Here, we show in lineage-tracing mouse models that although Wnt is essential for basal stem cell...

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Detalles Bibliográficos
Autores principales: Horton, Corrigan, Liu, Yueli, Wang, Jiawen, Green, Jonathan, Tsyporin, Jeremiah, Chen, Bin, Wang, Zhu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277819/
https://www.ncbi.nlm.nih.gov/pubmed/37172587
http://dx.doi.org/10.1016/j.stemcr.2023.04.003