Embryonic stem cell ERK, AKT, plus STAT3 response dynamics combinatorics are heterogeneous but NANOG state independent

Signaling is central in cell fate regulation, and relevant information is encoded in its activity over time (i.e., dynamics). However, simultaneous dynamics quantification of several pathways in single mammalian stem cells has not yet been accomplished. Here we generate mouse embryonic stem cell (ES...

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Detalles Bibliográficos
Autores principales: Reimann, Andreas, Kull, Tobias, Wang, Weijia, Dettinger, Philip, Loeffler, Dirk, Schroeder, Timm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277824/
https://www.ncbi.nlm.nih.gov/pubmed/37207650
http://dx.doi.org/10.1016/j.stemcr.2023.04.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277824/
https://www.ncbi.nlm.nih.gov/pubmed/37207650
http://dx.doi.org/10.1016/j.stemcr.2023.04.008

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