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Single-cell profiling of low-stage endometrial cancers identifies low epithelial vimentin expression as a marker of recurrent disease

BACKGROUND: Identification of aggressive low-stage endometrial cancers is challenging. So far, studies have failed to pinpoint robust features or biomarkers associated with risk of recurrence for these patients. METHODS: Imaging mass cytometry was used to examine single-cell expression of 23 protein...

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Detalles Bibliográficos
Autores principales: Lien, Hilde E., Berg, Hege F., Halle, Mari K., Trovik, Jone, Haldorsen, Ingfrid S., Akslen, Lars A., Krakstad, Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277918/
https://www.ncbi.nlm.nih.gov/pubmed/37146405
http://dx.doi.org/10.1016/j.ebiom.2023.104595