Cross-tissue omics analysis discovers ten adipose genes encoding secreted proteins in obesity-related non-alcoholic fatty liver disease

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a fast-growing, underdiagnosed, epidemic. We hypothesise that obesity-related inflammation compromises adipose tissue functions, preventing efficient fat storage, and thus driving ectopic fat accumulation into the liver. METHODS: To identify a...

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Detalles Bibliográficos
Autores principales: Darci-Maher, Nicholas, Alvarez, Marcus, Arasu, Uma Thanigai, Selvarajan, Ilakya, Lee, Seung Hyuk T., Pan, David Z., Miao, Zong, Das, Sankha Subhra, Kaminska, Dorota, Örd, Tiit, Benhammou, Jihane N., Wabitsch, Martin, Pisegna, Joseph R., Männistö, Ville, Pietiläinen, Kirsi H., Laakso, Markku, Sinsheimer, Janet S., Kaikkonen, Minna U., Pihlajamäki, Jussi, Pajukanta, Päivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277924/
https://www.ncbi.nlm.nih.gov/pubmed/37224770
http://dx.doi.org/10.1016/j.ebiom.2023.104620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277924/
https://www.ncbi.nlm.nih.gov/pubmed/37224770
http://dx.doi.org/10.1016/j.ebiom.2023.104620

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