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Cross-tissue omics analysis discovers ten adipose genes encoding secreted proteins in obesity-related non-alcoholic fatty liver disease
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a fast-growing, underdiagnosed, epidemic. We hypothesise that obesity-related inflammation compromises adipose tissue functions, preventing efficient fat storage, and thus driving ectopic fat accumulation into the liver. METHODS: To identify a...
Autores principales: | Darci-Maher, Nicholas, Alvarez, Marcus, Arasu, Uma Thanigai, Selvarajan, Ilakya, Lee, Seung Hyuk T., Pan, David Z., Miao, Zong, Das, Sankha Subhra, Kaminska, Dorota, Örd, Tiit, Benhammou, Jihane N., Wabitsch, Martin, Pisegna, Joseph R., Männistö, Ville, Pietiläinen, Kirsi H., Laakso, Markku, Sinsheimer, Janet S., Kaikkonen, Minna U., Pihlajamäki, Jussi, Pajukanta, Päivi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277924/ https://www.ncbi.nlm.nih.gov/pubmed/37224770 http://dx.doi.org/10.1016/j.ebiom.2023.104620 |
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