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Identification of cervical cancer stem cells using single-cell transcriptomes of normal cervix, cervical premalignant lesions, and cervical cancer

BACKGROUND: Cervical cancer is the fourth leading cause of mortality among gynecological malignancies. However, the identification of cervical cancer stem cells remains unclear. METHODS: We performed single-cell mRNA sequencing on ∼122,400 cells from 20 cervical biopsies, including 5 healthy control...

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Detalles Bibliográficos
Autores principales: Zhang, Tao, Zhuang, Liang, Muaibati, Munawaer, Wang, Dan, Abasi, Abuduyilimu, Tong, Qing, Ma, Ding, Jin, Lei, Huang, Xiaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277926/
https://www.ncbi.nlm.nih.gov/pubmed/37224771
http://dx.doi.org/10.1016/j.ebiom.2023.104612