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Exosomes from circ-Astn1-modified adipose-derived mesenchymal stem cells enhance wound healing through miR-138-5p/SIRT1/FOXO1 axis regulation

BACKGROUND: Wound healing impairment is a dysfunction induced by hyperglycemia and its effect on endothelial precursor cells (EPCs) in type 2 diabetes mellitus. There is increasing evidence showing that exosomes (Exos) derived from adipose-derived mesenchymal stem cells (ADSCs) exhibit the potential...

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Detalles Bibliográficos
Autores principales: Wang, Zhi, Feng, Cheng, Liu, Hao, Meng, Tian, Huang, Wei-Qing, Song, Ke-Xin, Wang, You-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277972/
https://www.ncbi.nlm.nih.gov/pubmed/37342222
http://dx.doi.org/10.4252/wjsc.v15.i5.476