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The Transposon-Encoded Protein TnpB Processes Its Own mRNA into ωRNA for Guided Nuclease Activity

TnpB is a member of the Obligate Mobile Element Guided Activity (OMEGA) RNA-guided nuclease family, is harbored in transposons, and likely functions to maintain the transposon in genomes. Previously, it was shown that TnpB cleaves double- and single-stranded DNA substrates in an RNA-guided manner, b...

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Detalles Bibliográficos
Autores principales: Nety, Suchita P., Altae-Tran, Han, Kannan, Soumya, Demircioglu, F. Esra, Faure, Guilhem, Hirano, Seiichi, Mears, Kepler, Zhang, Yugang, Macrae, Rhiannon K., Zhang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278001/
https://www.ncbi.nlm.nih.gov/pubmed/37272862
http://dx.doi.org/10.1089/crispr.2023.0015