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The Transposon-Encoded Protein TnpB Processes Its Own mRNA into ωRNA for Guided Nuclease Activity
TnpB is a member of the Obligate Mobile Element Guided Activity (OMEGA) RNA-guided nuclease family, is harbored in transposons, and likely functions to maintain the transposon in genomes. Previously, it was shown that TnpB cleaves double- and single-stranded DNA substrates in an RNA-guided manner, b...
Autores principales: | Nety, Suchita P., Altae-Tran, Han, Kannan, Soumya, Demircioglu, F. Esra, Faure, Guilhem, Hirano, Seiichi, Mears, Kepler, Zhang, Yugang, Macrae, Rhiannon K., Zhang, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278001/ https://www.ncbi.nlm.nih.gov/pubmed/37272862 http://dx.doi.org/10.1089/crispr.2023.0015 |
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