Identification of Macrocyclic Peptide Families from Combinatorial Libraries Containing Noncanonical Amino Acids Using Cheminformatics and Bioinformatics Inspired Clustering

[Image: see text] In the past decade, macrocyclic peptides gained increasing interest as a new therapeutic modality to tackle intracellular and extracellular therapeutic targets that had been previously classified as “undruggable”. Several technological advances have made discovering macrocyclic pep...

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Detalles Bibliográficos
Autores principales: Lee, Man-Ling, Farag, Sherif, Del Cid, Joselyn S., Bashore, Charlene, Hallenbeck, Kenneth K., Gobbi, Alberto, Cunningham, Christian N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278063/
https://www.ncbi.nlm.nih.gov/pubmed/37220419
http://dx.doi.org/10.1021/acschembio.3c00159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278063/
https://www.ncbi.nlm.nih.gov/pubmed/37220419
http://dx.doi.org/10.1021/acschembio.3c00159

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