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IFIH1 and DDX58 gene variants in pediatric rheumatic diseases

BACKGROUND: The IFIH1 gene codes the MDA5 protein and the DDX58 gene codes the RIG-I receptor. Both proteins are parts of the interferon (IFN) I signaling pathway and are responsible for antiviral defense and innate immune response. IFIH1 and DDX58 polymorphisms are associated with a spectrum of aut...

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Detalles Bibliográficos
Autores principales: Raupov, Rinat, Suspitsin, Evgeny, Belozerov, Konstantin, Gabrusskaya, Tatiana, Kostik, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278078/
https://www.ncbi.nlm.nih.gov/pubmed/37342449
http://dx.doi.org/10.5409/wjcp.v12.i3.107