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IFIH1 and DDX58 gene variants in pediatric rheumatic diseases
BACKGROUND: The IFIH1 gene codes the MDA5 protein and the DDX58 gene codes the RIG-I receptor. Both proteins are parts of the interferon (IFN) I signaling pathway and are responsible for antiviral defense and innate immune response. IFIH1 and DDX58 polymorphisms are associated with a spectrum of aut...
Autores principales: | Raupov, Rinat, Suspitsin, Evgeny, Belozerov, Konstantin, Gabrusskaya, Tatiana, Kostik, Mikhail |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278078/ https://www.ncbi.nlm.nih.gov/pubmed/37342449 http://dx.doi.org/10.5409/wjcp.v12.i3.107 |
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