Probing Regio- and Enantioselectivity in the Formal [2 + 2] Cycloaddition of C(1)-Alkyl Ammonium Enolates with β- and α,β-Substituted Trifluoromethylenones

[Image: see text] The isothiourea-catalyzed regio- and enantioselective formal [2 + 2] cycloaddition of C(1)-alkyl and C(1)-unsubstituted ammonium enolates with β- and α,β-substituted trifluoromethylenones has been developed. In all cases, preferential [2 + 2]-cycloaddition over the alternative [4 +...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yihong, Young, Claire M., Cordes, David B., Slawin, Alexandra M. Z., Smith, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278128/
https://www.ncbi.nlm.nih.gov/pubmed/37184337
http://dx.doi.org/10.1021/acs.joc.2c02688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278128/
https://www.ncbi.nlm.nih.gov/pubmed/37184337
http://dx.doi.org/10.1021/acs.joc.2c02688

Ejemplares similares