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Optimized Signal Peptide for Secretory Expression of Human Recombinant Somatropin in E. coli

Purpose: The human somatropin is a single-chain polypeptide with a pivotal role in various biological processes. Although Escherichia coli is considered as a preferred host for the production of human somatropin, the high expression of this protein in E. coli results in the accumulation of protein a...

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Detalles Bibliográficos
Autores principales: Ahmadi, Zeynab, Farajnia, Safar, Farajzadeh, Davoud, Pouladi, Naser, Pourvatan, Neda, Karbalaeimahdi, Mohammad, Shayegh, Fahime, Arya, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278209/
https://www.ncbi.nlm.nih.gov/pubmed/37342372
http://dx.doi.org/10.34172/apb.2023.037