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Optimized Signal Peptide for Secretory Expression of Human Recombinant Somatropin in E. coli
Purpose: The human somatropin is a single-chain polypeptide with a pivotal role in various biological processes. Although Escherichia coli is considered as a preferred host for the production of human somatropin, the high expression of this protein in E. coli results in the accumulation of protein a...
Autores principales: | Ahmadi, Zeynab, Farajnia, Safar, Farajzadeh, Davoud, Pouladi, Naser, Pourvatan, Neda, Karbalaeimahdi, Mohammad, Shayegh, Fahime, Arya, Maryam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tabriz University of Medical Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278209/ https://www.ncbi.nlm.nih.gov/pubmed/37342372 http://dx.doi.org/10.34172/apb.2023.037 |
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