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The Impact of Single Nucleotide Polymorphisms on the Pharmacokinetics of Tacrolimus in Kidney Allograft Recipients of Northern-West, Iran

Purpose: Calcineurin inhibitors (CNIs) such as tacrolimus are a major immunosuppressive therapy after renal transplantation, which inhibit cytokine expression. The pharmacokinetics of such drugs is influenced by cytochrome P450 (CYP) enzymes, multi-drug resistance-1 (MDR-1), and C25385T pregnane X r...

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Detalles Bibliográficos
Autores principales: Jabbari Hagh, Elaheh, Mousavi, Ali, Hejazian, Seyyedeh Mina, Haghi, Mehdi, Esfahanian, Samaneh, Ahmadian, Elham, Zununi Vahed, Sepideh, Ardalan, Mohammadreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278212/
https://www.ncbi.nlm.nih.gov/pubmed/37342387
http://dx.doi.org/10.34172/apb.2023.038