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Iron Withdrawal with DIBI, a Novel 3-Hydroxypyridin-4-One Chelator Iron-Binding Polymer, Attenuates Macrophage Inflammatory Responses

Purpose: Iron is an essential trace element for the inflammatory response to infection. In this study, we determined the effect of the recently developed iron-binding polymer DIBI on the synthesis of inflammatory mediators by RAW 264.7 macrophages and bone marrow-derived macrophages (BMDMs) in respo...

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Detalles Bibliográficos
Autores principales: Ghassemi-Rad, Javad, Fernando, Wasundara, Holbein, Bruce E., Hoskin, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278213/
https://www.ncbi.nlm.nih.gov/pubmed/37342371
http://dx.doi.org/10.34172/apb.2023.040