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Regulon analysis identifies protective FXR and CREB5 in proximal tubules in early diabetic kidney disease
Diabetic kidney disease (DKD) is the most common complication of diabetes mellitus and a leading cause of kidney failure worldwide. Despite its prevalence, the mechanisms underlying early kidney damage in DKD remain poorly understood. In this study, we used single nucleus RNA-seq to construct gene r...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278299/ https://www.ncbi.nlm.nih.gov/pubmed/37337149 http://dx.doi.org/10.1186/s12882-023-03239-6 |