Regulon analysis identifies protective FXR and CREB5 in proximal tubules in early diabetic kidney disease

Diabetic kidney disease (DKD) is the most common complication of diabetes mellitus and a leading cause of kidney failure worldwide. Despite its prevalence, the mechanisms underlying early kidney damage in DKD remain poorly understood. In this study, we used single nucleus RNA-seq to construct gene r...

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Detalles Bibliográficos
Autores principales: Shi, Wanting, Le, Weibo, Tang, Qiaoli, Shi, Shaolin, Shi, Jingsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278299/
https://www.ncbi.nlm.nih.gov/pubmed/37337149
http://dx.doi.org/10.1186/s12882-023-03239-6

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