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Single-cell transcriptome profiling of sepsis identifies HLA-DR(low)S100A(high) monocytes with immunosuppressive function

BACKGROUND: Sustained yet intractable immunosuppression is commonly observed in septic patients, resulting in aggravated clinical outcomes. However, due to the substantial heterogeneity within septic patients, precise indicators in deciphering clinical trajectories and immunological alterations for...

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Detalles Bibliográficos
Autores principales: Yao, Ren-Qi, Zhao, Peng-Yue, Li, Zhi-Xuan, Liu, Yu-Yang, Zheng, Li-Yu, Duan, Yu, Wang, Lu, Yang, Rong-Li, Kang, Hong-Jun, Hao, Ji-Wei, Li, Jing-Yan, Dong, Ning, Wu, Yao, Du, Xiao-Hui, Zhu, Feng, Ren, Chao, Wu, Guo-Sheng, Xia, Zhao-Fan, Yao, Yong-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278311/
https://www.ncbi.nlm.nih.gov/pubmed/37337301
http://dx.doi.org/10.1186/s40779-023-00462-y