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Scutellaria baicalensis enhances 5-fluorouracil-based chemotherapy via inhibition of proliferative signaling pathways

Fluoropyridine-based chemotherapy remains the most widely used treatment for colorectal cancer (CRC). In this study, we investigated the mechanism by which the natural product Scutellaria baicalensis (Huang Qin; HQ) and one of its main components baicalin enhanced 5-fluorouracil (5-FU) antitumor act...

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Detalles Bibliográficos
Autores principales: Liu, Haizhou, Liu, Hui, Zhou, Zhiyi, Chung, Jessica, Zhang, Guojing, Chang, Jin, Parise, Robert A., Chu, Edward, Schmitz, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278337/
https://www.ncbi.nlm.nih.gov/pubmed/37337282
http://dx.doi.org/10.1186/s12964-023-01156-7