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Hypoxic lung adenocarcinoma‐derived exosomal miR‐1290 induces M2 macrophage polarization by targeting SOCS3

BACKGROUND: Exosomes are critical mediators of tumor cell‐microenvironment cross talk. However, the mechanisms by which hypoxic Lung adenocarcinoma (LUAD)‐derived exosomes modulate macrophage polarization remain largely unknown. The aim of this study was to investigate the effects of hypoxic LUAD‐de...

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Detalles Bibliográficos
Autores principales: Gu, Jiahui, Yang, Shengrui, Wang, Xueying, Wu, Yining, Wei, Jia, Xu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278512/
https://www.ncbi.nlm.nih.gov/pubmed/37081748
http://dx.doi.org/10.1002/cam4.5954